The effect of n-3 PUFAs in the prevention of sudden heart death in patients after myocardial infarction is undeniable.
Patients who did not suffer any coronary disease are exclusively advised to change their diet, replacing saturated and trans fats by polyunsaturated fats, consuming fish at least twice a week. Patients who have already suffered coronary disease are advised to take, moreover, dietary supplements of Omega 3 but under medical supervision.
W-3 fatty acids intake is related to a decrease of cardiovascular disease risk, reducing the death risk associated with this sort of pathologies.
N-3 PUFAs are a promising preventive therapy for cardiovascular diseases, and they represent a safe and effective method for sudden death prevention.
Diets high in MUFAs and n-3 PUFAs produce a significant decrease of blood pressure without modifying glucose and insulin plasmatic concentrations.
Omega 3 fatty acids intake haves a protective effect against acute myocardial infarction. However, results show that there is a threshold value and once it is exceeded, the protection does not increase.
The n-3 fatty acids found in fish are strongly associated with a reduced risk of sudden death among men without evidence of prior cardiovascular disease.
A simple and safe treatment with n-3 PUFA can provide a small beneficial advantage in terms of mortality and admission to hospital for cardiovascular reasons in patients with heart failure in a context of usual care.
These findings provide firm evidence that fish oil consumption directly or indirectly affects cardiac electrophysiology in humans. Potential mechanisms such as effects on the sinus node, ventricular efficiency, or autonomic function deserve further investigation